Honestly, a girl I dated a coupple years ago, I was like 21-22, was allergic to my semen. Her vajayjay would puff up and swell and she would be in pain for like 30 minutes. I'm not joking about this, she had to see a doctor and everything, and it is an extremely rare condition. Her body "rejected" it, and in some cases the MD said it could be fatal.
Where I come from, we call those women lesbians.