Depends what part you are talking about. 2 miles down 74 and in, those neighborhoods are thriving. The neighborhoods don't really start to go downhill until you get around the original coliseum.
Plaza-Midwood and Elizabeth flank the sides of 74 closer to downtown and they're doing very, very well.
That's a good distance away from the old retail areas on Independence. Behind the Coliseum is Grier Heights, that area is one of the worst crime areas in Charlotte.