Wow. This thread sucks. One off game against the Saints, in the dome after they lost on MNF, and the sky is falling? That is just sad. I am upset too, but really??? I wanted to win this game as much as the next guy, but we are STILL a good team. Our defense is still one of the best in the league. We will cause trouble in the playoffs, and you people suck.
If they moved the files when compressing, then the slow down may be from it trying to locate the data. Try reentering the formulas to recreate the data paths. You may also just copy the data into a new excel file, and start again with new uncompressed files.
Please note: I am not an IT person, but I do work with excel quite a bit.