Jacksonville makes sense. Weak fanbase, small market, bad team. They could move the team to LA and put them in the NFC West. Move the St. Louis Rams to the AFC South. Everything makes sense geographically, everyone's happy.
The only issue with moving the Rams to the AFC South is if they themselves relocate to LA. Then where do they go?
As it stands if the Jags move to LA - which I doubt if their owner is sincere - then wouldn't it be easier to move them to the AFC West?
I guess the issue there is the rivalries between those four teams and tradition, but putting the LA Jaguars in that division might be better. Though they could keep them in the AFC South. It isn't like the divisions are set up exactly correct geographically anyway - eg.Rams in the West, Cowboys in the East etc.