I'm in Irvine now. Maybe throw some out for next time i'm there?
You've had a Sculpin, which is a fantastic start. You have to check out the Ballast Point brewery in Little Italy. Sculpin is their most popular but they have so many good stouts and porters too. Victory at Sea might be the best poo they brew.
Green Flash in Mira Mesa is just phenomenal.
Modern Times in Point Loma would round out my top 3.
Then of course, there's always Stone. The brewery and gardens they have in Escondido is a must. Plus they have the best bathrooms in all of the SD breweries. Go straight for the Oaked Arrogant Bastard or the Ruination.
I'm thirsty now.
p.s. To get to Stone from the 5, you'd have to take the 78 highway east, known locally as the "hop highway" as there are over 15 breweries that line the highway from Oceanside to Escondildo.
That's my .02 /end beer nerdgasm
fug the steelers.