i've heard sierra nevada is out of this world cool. Also heard they are building an ampitheatre so asheville folks will have two cool places to go for big acts.
the breweries i like have already been stated. another cool bar to go to is bier gardens.
We're already overrun with venues. Just went to the first major show at New Mountain Amphitheater this weekend, which was really nice and right in downtown.
I kinda feel bad for Pisgah and their amphitheater. I think they're going to feel these new outdoor venues (in town) that are opening the most.