I am very much a football noob but I am doing my best to learn as much as I can about the pro-level game.
I started seriously following the Panthers during the 2007 season when I began to seriously like football so I am aware I lack much of the knowledge that you veteran fans have. That said I will do my best to be a true Panther and football fan.
any conclusion determined through scientific process should be thought of as, "the best we know about this so far." it's foolish and arrogant to assume that anything is ever known to its full completeness. someone will always be uncovering a new layer of understanding. that's what makes it all so damn cool. there's always more to learn about any topic.
While I in principle agree with your overarching point 2+2=4 is an example of something that is known to it's "full completeness."