Jump to content

  • Welcome!

    Register and log in easily with Twitter or Google accounts!

    Or simply create a new Huddle account. 

    Members receive fewer ads , access our dark theme, and the ability to join the discussion!

     

Why Weed Makes You...hey what the f*ck are you doing to those rats?

The Pieyed Piper

By The Pieyed Piper,
in Huddle Lounge

Recommended Posts

The Pieyed Piper Newbie

The Pieyed Piper

Posted
Posted

http://gizmodo.com/5889856/why-weed-makes-youyouhuh?tag=the-stoner-channel

A duo of researchers, Giovanni Marsicano of the University of Bordeaux, France, and Xia Zhang of the University of Ottawa Institute of Mental Health Research, have been credited with the discovery published today in the journal Cell. Previously, scientists believed that THC "loosened" synapses in the hippocampus, resulting in memory loss. But contrary to convention, the effect isn't rooted in the drug's effect on the neurons alone but also on an undiscovered reaction between THC and non-neuronal cells known as astrocytes.

Astrocytes used to be thought of simply "support" cells that helped neurons function. However, the team's research showed that these cells also produce a chemical called AMPA when they interact with THC and it's the AMPA compound that can mitigate or enhance the looseness of the neuron's synapse.

To prove the hypothesis, the team employed three types of rats with various alterations to their neurons' CB1 receptors (these receptors bind with THC and activate the cells when THC is present). The first set lacked receptors on cells that produce the neurotransmitter glutamate, the second set lacked receptors on cells that create the neurotransmitter GABA, and the third set lacked them on the AMPA-producing astrocytes. Basically, if the cells lacked this receptor, THC wouldn't affect them and they wouldn't produce the associated chemical.

The team inserted electrodes into the anesthetized rats' brains, got them blunted, and then recorded the results. The glutamate and GABA sets of rats responded in the same way that normal rats would—high as poo and terrible short-term memory. The AMPA-less rats however were unaffected.

comments...

Google also reports that girls like butt sex. I tried, they don't.
Link to comment
Share on other sites
bleys Newbie

bleys

Posted
Posted

One set of rats went out and got a job while the other set of rats stayed home watching Scooby-Doo and ate Lays potato chips.

says the alcoholic who beats his wife and kids before proceeding to kill a family drinking and driving after losing his job due to a physical addiction.....

Link to comment
Share on other sites

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • PMH4OWPW7JD2TDGWZKTOYL2T3E.jpg

  • Topics

  • Posts

    • PantherChris
      Official NHL Playoffs Thread 2024

      By PantherChris · Posted

      Yeah the Caps didn't belong lol
    • frankw
      Every Xavier Legette target 2023

      By frankw · Posted

      I know we're in the hopium phase of the year right now but this is all over the game film that every defense we face is going to be waiting for. If Bryce keeps doing this sooner or later we are going to be stuck arguing over why this or that receiver sucks because they can't bail out Bryce all the time. Legette would just be next in line. Bryce is a first overall pick. He's got to figure out how to get some more torque out of his arm. These yarns about his frame and this and that just seem like an excuse to justify him not wanting to lift weights. He's got to match the output of his offensive counterparts who have been putting in the work.
    • d-dave
      Where would the Panthers be if they sat Bryce Young last season?

      By d-dave · Posted

      Well, if we'd sat Bryce then we'd have gone 17~0 on the way to Superb Owl win!  Of course right? Honestly, it's one of those Schrodinger's Cat situations.  There are an infinite number of possibilities that it could have been between: Worse and Better.   Dalton would have looked better.  We'd have won more games.  Reich would probably be going into year two with Scott Fitterer at GM.  Would we be a be a better team? We would have zero idea if Bryce was the dude, kind of where we are now.  Except Bryce would not have had as much adversity.  With QBs in the NFL, you don't have much time to evaluate.  You used to be able to sit guys for a year or two, but now a days, you are up and playing week 1. I think we'd be in worse shape honestly.  I like how things are going right now under D&D.  I am not sure Fitterer would have done any better in FA or the Draft or if Reich would have shown his coaching acumen any better in 2024. So instead of changing the past, we have to keep looking forward.  Learn the lessons from the past, but keep moving forward.
×
×
  • Create New...