100% if your employer cannot take a joke then its not the work environment you want to get into.
I did this to at my last job interview. I HATE typical interview questions - yet I do get their importance. They asked the typical "what is your biggest weakness?" question. I responded, rolling my eyes and said "I work too hard, care too much and sometimes can be too invested in my job" Took a second for them to realized I was joking but basically from that point on I knew I nailed it